If concomitant use is warranted, carefully observe the client, particularly during therapy initiation and dose adjustment. Discontinue DILAUDID INJECTION if serotonin syndrome is suspected.
Breastfeeding considerations: Nonopioid analgesic brokers are preferable for breastfeeding women who have to have pain management medications during the peripartum period of time and for surgical methods beyond the postpartum section.[six]
Hydromorphone also necessitates careful administration in sufferers using selective serotonin reuptake inhibitors or tricyclic antidepressants due to potential hazard of serotonin syndrome.
Opioids are actually shown to obtain various effects on factors from the immune system in in vitro and animal types. The scientific significance of such conclusions is unknown. All round, the effects of opioids look like modestly immunosuppressive.
Hydromorphone hydrochloride injection (high potency formulation) ought to hardly ever be administered to opioid-naïve people. The minimum effective dose of hydromorphone needs to be used for your shortest duration that aligns with the individual's remedy targets.
It is critical that you choose to understand the rules in the Opioid Analgesic REMS application to prevent addiction, abuse, and misuse of hydromorphone. This medicine should also appear with a Medication Manual. Read and comply with these Directions carefully. Browse it again Just about every time you refill your prescription in case There exists new information.
If you utilize opioid medicine while you are Expecting, your infant could turn into depending on the drug. This can cause life-threatening withdrawal signs and symptoms in the newborn after it is born. Babies born dependent on opioids may need health-related treatment method for a number of months.
This doc does not contain all achievable side effects and others could take place. Examine with your medical professional For extra information about dilaudid iv to oral equivalent side effects.
Check patients with a heritage of seizure Issues for worsened seizure control during DILAUDID INJECTION therapy.
The qualifications possibility of major delivery defects and miscarriage with the indicated inhabitants is unknown. All pregnancies have a background chance of start defect, decline, or other adverse outcomes.
Use precisely as directed by your physician. Learn the correct solution to give injections. When you have any questions about making use of this medication effectively, seek advice from your medical professional or pharmacist.
Both of such drugs also can result in overdose and are really unsafe for children. Continue to keep your medication locked and absent from any kids in your house. Because hydromorphone is so potent, it may be fatal if a youngster takes just one ER tablet.
Misuse and abuse of DILAUDID INJECTION increases risk of overdose, which can lead to central nervous system and respiratory depression, hypotension, seizures, and death. The risk is increased with concurrent abuse of DILAUDID INJECTION with alcohol and/or other CNS depressants.
Patients at high hazard of DILAUDID INJECTION abuse incorporate those with a heritage of prolonged use of any opioid, together with merchandise containing hydromorphone, These with a history of drug or alcohol abuse, or those who use DILAUDID INJECTION in combination with other abused drugs.